Found 47 matching trials
Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH) PHASE3 Combination therapy in pulmonary arterial hypertension (PAH) has been the s...
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Providence Medical Foundation
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A Study of Two Macitentan Formulations in Healthy Adult Participants PHASE1 The purpose of this study is to evaluate the bioequivalence of macitentan o...
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An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients. PHASE3 The aim of this open-label (OL) trial is to study the long-term use of maci...
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Massachusetts General Hospital Heart Center
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A Clinical Study to Find Out if Macitentan is Effective and Safe in Japanese Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH). PHASE3 The endothelin receptor antagonist macitentan showed significant improvemen...
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Fukuoka University Nishijin Hospital
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Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument PHASE3 SYMPHONY is prospective, multi-center, open-label, single-arm, Phase 3b psy...
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Cardiovascular Associates of the Southeast, LLC
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A Pulmonary Arterial Hypertension Study With Macitentan to Validate the PAH-SYMPACT™ in France, Italy and Spain PHASE3 Prospective, multi-center, open-label, single-arm, Phase 3b psychometric va...
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Hôpital de Haut Levêque
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Clinical Study to Investigate the Effect of Macitentan on the Concentrations of Rosuvastatin in the Blood of Healthy Male Subjects PHASE1 The aim of this Phase 1 trial is to study a potential drug-drug interaction...
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CRS Clinical Research Services Mannheim
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Extension of the Psychometric Validation Study ORCHESTRA in Patients With PAH PHASE3 Prospective, multi-center, open-label, single-arm, Phase 3b extension study...
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Hôpital Louis Pradel
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A Study of Macitentan and Tadalafil as a Fixed Dose Combination and the Free Combination in Healthy Adult Participants PHASE1 The purpose of this study is to demonstrate bioequivalence on the primary p...
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Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension PHASE3 The main objective of the AC 055 303/SERAPHIN OL study, which will follow t...
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University of Alabama at Birmingham
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